Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 7/20 | 0.51 |
| ▸ | NOS2 | P35228 | 7/20 | 0.51 |
| ▸ | NOS3 | P29474 | 5/20 | 0.51 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ARG2 | P78540 | 4/20 | 0.42 |
| ▸ | ARG1 | P05089 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713674 | 1.00 | NOS1 (0.51) | NOS1NOS2NOS3DDAH1GSR | |
| SCHEMBL9713668 | 1.00 | NOS1 (0.51) | NOS1NOS2NOS3DDAH1GSR | |
| SCHEMBL5059526 | 0.81 | NOS2 (0.54) | NOS1NOS2NOS3GSRCYP2C19 | |
| SCHEMBL5520220 | 0.81 | NOS2 (0.54) | NOS1NOS2NOS3GSRCYP2C19 | |
| SCHEMBL3117359 | 0.81 | NOS2 (0.54) | NOS1NOS2NOS3GSRCYP2C19 | |
| SCHEMBL15157561 | 0.81 | NOS2 (0.47) | NOS1NOS2NOS3GSRCYP2C19 | |
| SCHEMBL18883517 | 0.77 | NOS1 (0.58) | NOS1NOS2NOS3DDAH1GSR | |
| SCHEMBL18196767 | 0.77 | KDM4C (0.50) | GRIK1 | |
| SCHEMBL11190508 | 0.76 | NOS2 (0.67) | NOS1NOS2NOS3DDAH1GSR | |
| SCHEMBL1331744 | 0.76 | GSR (0.52) | NOS1NOS2NOS3GSRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253245-B1 | BIOLOGICALLY ACTIVE PEPTIDES TAN-866 | Takeda Chemical Industries, Ltd. (JP) | 1992-10-14 | — | — | EP | disclosed |