Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | USP5 | P45974 | 1/20 | 0.37 |
| ▸ | USP4 | Q13107 | 1/20 | 0.37 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713901 | 0.84 | ABCB11 (0.43) | SMN1; SMN2ABCB11CNR1TP53HPGD | |
| SCHEMBL9643164 | 0.82 | ABCB11 (0.62) | SMN1; SMN2ABCB11ALOX15TP53ATM | |
| SCHEMBL10502162 | 0.81 | PTGER4 (0.47) | SMN1; SMN2ABCB11ALOX15CNR1TP53 | |
| SCHEMBL10504035 | 0.78 | ABCB11 (0.44) | SMN1; SMN2ABCB11ALOX15CNR1HPGD | |
| SCHEMBL9449155 | 0.77 | ABCB11 (0.52) | SMN1; SMN2ABCB11ALOX15HPGDATM | |
| SCHEMBL9641852 | 0.76 | ABCB11 (0.48) | SMN1; SMN2ABCB11ATMMEN1KMT2A | |
| SCHEMBL9643189 | 0.76 | ABCB11 (0.60) | SMN1; SMN2ABCB11ALOX15TP53LMNA | |
| SCHEMBL9643528 | 0.76 | ABCB11 (0.51) | SMN1; SMN2ABCB11ALOX15TP53ATM | |
| SCHEMBL9642327 | 0.76 | ABCB11 (0.51) | SMN1; SMN2ABCB11ALOX15TP53ATM | |
| SCHEMBL9643180 | 0.76 | CHRM1 (0.49) | SMN1; SMN2ABCB11TP53HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |