Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28574517 | 0.79 | PLAU (0.59) | PLAUCTDSP1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL8411722 | 0.79 | PLAU (0.53) | PLAUCTDSP1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL31634586 | 0.79 | PLAU (0.53) | PLAUCTDSP1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL28430736 | 0.79 | CYP1A2 (0.43) | ALDH1A1CYP3A4HSD17B10ALOX15HIF1A | |
| SCHEMBL18051604 | 0.78 | PLAU (0.44) | PLAUCTDSP1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL28432170 | 0.76 | CYP2A6 (0.40) | ALDH1A1CYP3A4HSD17B10CASP1ALOX15 | |
| SCHEMBL2445157 | 0.75 | ALDH1A1 (0.57) | PLAUCTDSP1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL8121539 | 0.73 | ALDH1A1 (0.55) | PLAUCTDSP1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL5028738 | 0.72 | CASP6 (0.54) | PLAUCTDSP1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL9697851 | 0.72 | TUBB4A (0.50) | ALDH1A1TDP1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151540-A | THIO CARBAMATES AND THEIR DERIVATIVES | HOECHST CELANESE CORPORATION (US) | 1992-09-29 | — | — | US | claimed |
| EP-0269434-A1 | Method for producing aminothiophenols and their derivatives | HOECHST CELANESE CORPORATION (US) | 1988-06-01 | — | — | EP | claimed |
| US-5157142-A | THIOCARBAMATES AND THEIR DERIVATIVES | HOECHST CELANESE CORPORATION (US) | 1992-10-20 | — | — | US | disclosed |
| US-5151540-A | THIO CARBAMATES AND THEIR DERIVATIVES | HOECHST CELANESE CORPORATION (US) | 1992-09-29 | — | — | US | disclosed |
| EP-0269434-A1 | Method for producing aminothiophenols and their derivatives | HOECHST CELANESE CORPORATION (US) | 1988-06-01 | — | — | EP | disclosed |
| EP-0251552-A2 | Process for producing aminothiophenols and their derivatives | CELANESE CORPORATION (US) | 1988-01-07 | — | — | EP | disclosed |