Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | TDP2 | O95551 | 2/20 | 0.46 |
| ▸ | NSD2 | O96028 | 2/20 | 0.46 |
| ▸ | BCL2 | P10415 | 4/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713431 | 0.86 | BCL2 (0.54) | IDO1CDC25ACDC25BMAOAMAOB | |
| SCHEMBL9628282 | 0.84 | IDO1 (0.61) | IDO1CDC25ACDC25BTDP2NSD2 | |
| SCHEMBL30003034 | 0.84 | IDO1 (0.61) | IDO1CDC25ACDC25BTDP2NSD2 | |
| SCHEMBL9713584 | 0.82 | IDO1 (0.52) | IDO1CDC25ACDC25BTDP2NSD2 | |
| SCHEMBL9713573 | 0.81 | MAOA (0.55) | MAOAMAOBBCL2MCL1S100A4 | |
| SCHEMBL9713488 | 0.81 | IDO1 (0.57) | IDO1CDC25ACDC25BTDP2NSD2 | |
| SCHEMBL9643160 | 0.80 | MAOA (0.58) | IDO1CDC25ACDC25BMAOAMAOB | |
| SCHEMBL9713721 | 0.78 | P4HB (0.44) | IDO1MAOAMAOBNSD2BCL2 | |
| SCHEMBL7807732 | 0.77 | IDO1 (0.61) | IDO1CDC25ACDC25BTDP2NSD2 | |
| SCHEMBL9713793 | 0.77 | CDC25B (0.53) | IDO1CDC25ACDC25BMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |