SCHEMBL9628282

SCHEMBL9628282

COC1=CC(=O)c2cc(Cl)ccc2C1=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.61
CDC25A P30304 1/20 0.61
CDC25B P30305 1/20 0.61
TDP2 O95551 2/20 0.54
NSD2 O96028 2/20 0.54
PTPN1 P18031 2/20 0.47
S100A4 P26447 3/20 0.47
GAPDH P04406 2/20 0.44
HKDC1 Q2TB90 3/20 0.43
HSP90AA1 P07900 1/20 0.41
CES2 O00748 2/20 0.41
CES1 P23141 2/20 0.41
PAX8 Q06710 1/20 0.40
ATG4B Q9Y4P1 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30003034 1.00 IDO1 (0.61) IDO1CDC25ACDC25BTDP2NSD2
SCHEMBL7807732 0.93 IDO1 (0.61) IDO1CDC25ACDC25BTDP2NSD2
SCHEMBL9713780 0.84 IDO1 (0.50) IDO1CDC25ACDC25BTDP2NSD2
SCHEMBL9713379 0.83 S100A4 (0.44) IDO1CDC25ACDC25BTDP2NSD2
SCHEMBL9629343 0.82 CDC25B (0.51) IDO1CDC25ACDC25BTDP2NSD2
SCHEMBL31371001 0.81 TDP2 (0.47) IDO1CDC25ACDC25BTDP2NSD2
SCHEMBL5822222 0.81 IDO1 (0.62) IDO1CDC25ACDC25BTDP2NSD2
SCHEMBL9627801 0.81 CDC25A (0.62) IDO1CDC25ACDC25BTDP2NSD2
SCHEMBL30003084 0.81 IDO1 (0.62) IDO1CDC25ACDC25BTDP2NSD2
SCHEMBL30003368 0.80 IDO1 (0.56) IDO1CDC25ACDC25BTDP2NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11613509-B2 Radical polymerization control agent and radical polymerization control method KAWASAKI KASEI CHEMICALS LTD. (JP) 2023-03-28 US disclosed
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed
US-20210122692-A1 RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD KAWASAKI KASEI CHEMICALS LTD. (JP) 2021-04-29 US disclosed
CN-110891980-A Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2020-03-17 CN disclosed
US-5155132-A Nonsteroidal antiinflammatory agents; treating psoriasis SYNTEX (U.S.A.) INC. (US) 1992-10-13 US disclosed
US-5134161-A Enzyme inhibitors for skin disorders, antiinflammatory agents SYNTEX (U.S.A.) INC. (US) 1992-07-28 US disclosed
US-5091558-A Topical administeration SYNTEX (U.S.A.) INC. (US) 1992-02-25 US disclosed
US-5089657-A Topical antiinflammatory agents SYNTEX (U.S.A.) INC. (US) 1992-02-18 US disclosed
US-4786652-A TOPICAL ADMINISTRATION SYNTEX (U.S.A.) INC. (US) 1988-11-22 US disclosed
EP-0282006-A1 Naphtalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1988-09-14 EP disclosed
EP-0282056-A2 Naphthalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1988-09-14 EP disclosed
EP-0150831-B1 NAPHTHALENE ANTI-PSORIATIC AGENTS SYNTEX (U.S.A.) INC. (US) 1988-08-10 EP disclosed
US-4758587-A Naphthalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1988-07-19 US disclosed
EP-0150831-A2 Naphthalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1985-08-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11613509-B2 Radical polymerization control agent and radical polymerization control method PPOX, NOX4, CROCC IDO1 2251/4885CDC25A 732/4885CDC25B 807/4885
US-20210122692-A1 RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD PPOX, NOX4, CROCC IDO1 2251/4885CDC25A 732/4885CDC25B 807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.