Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714207 | 0.85 | MMP1 (0.48) | MMP1MMP3MMP9MMP13 | |
| SCHEMBL7837093 | 0.82 | MMP1 (0.44) | GRIK1MMP1MMP3MMP9MMP13 | |
| SCHEMBL7837095 | 0.82 | MMP1 (0.44) | GRIK1MMP1MMP3MMP9MMP13 | |
| SCHEMBL6987281 | 0.82 | MMP3 (0.45) | GRIK1MMP1MMP3MMP9REN | |
| SCHEMBL6659520 | 0.82 | MMP3 (0.45) | GRIK1MMP1MMP3MMP9REN | |
| SCHEMBL6943292 | 0.82 | MMP3 (0.45) | GRIK1MMP1MMP3MMP9REN | |
| SCHEMBL6659518 | 0.82 | MMP3 (0.45) | GRIK1MMP1MMP3MMP9REN | |
| SCHEMBL6943287 | 0.82 | MMP3 (0.45) | GRIK1MMP1MMP3MMP9REN | |
| SCHEMBL7827850 | 0.79 | MMP1 (0.46) | GRIK1MMP1MMP3MMP9MMP13 | |
| SCHEMBL7853162 | 0.79 | MMP1 (0.46) | GRIK1MMP1MMP3MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497192-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-08-05 | — | — | EP | disclosed |