SCHEMBL97139

SCHEMBL97139

[CH2]c1cc(C)c(C)c(C)c1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.32
TUBB1 Q9H4B7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28040368 0.97 RAPGEF4 (0.30) RAPGEF4
SCHEMBL9540860 0.80 ALDH1A1 (0.31)
SCHEMBL4753068 0.73 SOS1 (0.31)
SCHEMBL3293550 0.73 CA1 (0.58)
SCHEMBL5610142 0.73 ALDH1A1 (0.58)
SCHEMBL1007834 0.73 CYP3A4 (0.52) RAPGEF4
SCHEMBL395085 0.71 CYP3A4 (0.33)
SCHEMBL28891533 0.71 MEN1 (0.35)
SCHEMBL1551822 0.69 RAPGEF4 (0.59) RAPGEF4
SCHEMBL28951 0.69 RAPGEF4 (0.59) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106103463-B Bridging type nucleosides and nucleotide 国立大学法人大阪大学 2018-11-30 CN claimed
EP-3109254-B1 CROSSLINKED NUCLEOSIDE AND NUCLEOTIDE UNIV OSAKA (JP) 2018-04-11 EP claimed
EP-1152009-B2 NOVEL NUCLEOSIDES AND OLIGONUCLEOTIDE ANALOGUES DAIICHI SANKYO CO LTD (JP) 2017-09-06 EP claimed
US-7335765-B2 Nucleoside and oligonucleotide analogues DAIICHI SANKYO COMPANY, LIMITED (JP) 2008-02-26 US claimed
EP-3904360-B1 NOVEL TETRAARYLBORATE COMPOUND, CATALYST COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFIN BY USING SAME SABIC SK NEXLENE COMPANY PTE LTD (SG) 2024-07-03 EP disclosed
US-20240208999-A1 HETEROCYCLIC COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-06-27 US disclosed
CN-113677686-B Novel tetraarylborate compounds, catalyst compositions comprising the same, and process for preparing ethylene homopolymers or copolymers of ethylene and alpha-olefins by using the same 沙特基础工业爱思开NEXLENE私人有限公司 2024-06-11 CN disclosed
CN-113387055-B Film, method for producing film, and bag 住友化学株式会社 2024-06-07 CN disclosed
EP-4370507-A1 HYDROGENATED QUINOXALINES Otsuka Pharmaceutical Co., Ltd. (JP) 2024-05-22 EP disclosed
WO-2024101446-A1 MODIFIED NUCLEOSIDE HAVING GUANIDINO STRUCTURE IN BRIDGED PART AND METHOD FOR PRODUCING OLIGONUCLEOTIDE USING SAME ルクサナバイオテク株式会社 2024-05-16 WO disclosed
WO-2024101258-A1 COMPOUND, POLYMERIZABLE COMPOSITION, ADHESIVE, RESIN CURED PRODUCT, MOLDED ARTICLE, FILM, PRESSURE-SENSITIVE ADHESIVE, AND METHOD FOR PRODUCING COMPOUND 三井化学株式会社 2024-05-16 WO disclosed
CN-112513062-B Oligonucleotide-containing small cell lung cancer therapeutic agent 国立大学法人大阪大学 2024-05-10 CN disclosed
US-4487772-A CARDIOTONIC AGENTS OTSUKA PHARMACEUTICAL CO. LTD. (JP) 1984-12-11 US disclosed
US-4468402-A Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-08-28 US disclosed
US-4455430-A ANTITUMOR AGENTS, MICROCIDES THE UPJOHN COMPANY (US) 1984-06-19 US disclosed
US-4454130-A CARDIOTONIC, HYPOTENSIVE AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-06-12 US disclosed
US-RE31578-E ANTITUMOR AGENTS, BACTERICIDES THE UPJOHN COMPANY (US) 1984-05-01 US disclosed
US-4298744-A CHLORINATION OF ISOMERIC ANALOG THE UPJOHN COMPANY (US) 1981-11-03 US disclosed
US-4275214-A ANALOGS OF TRICHOLOMIC ACID USEFUL AS INTERMEDIATES IN THE PREPARATION OF AT-125 THE UPJOHN COMPANY (US) 1981-06-23 US disclosed
US-4256898-A INTERMEDIATES FOR MAKING (ALPHAS, 5S)-ALPHA-AMINO-3-CHLORO-2-ISOXAZOLINE-5-ACETIC ACID (AT-125) THE UPJOHN COMPANY (US) 1981-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240208999-A1 HETEROCYCLIC COMPOUND AHR, PDGFRA, PDGFRB RAPGEF4 1430/4885TUBB1 4378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.