SCHEMBL4753068

SCHEMBL4753068

[CH2]c1cc(C)c(F)c(C)c1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL97139 0.73 RAPGEF4 (0.32)
SCHEMBL13550041 0.73 RAPGEF4 (0.37) SOS1
SCHEMBL662008 0.73 RAPGEF4 (0.46)
SCHEMBL7025202 0.73 RAPGEF4 (0.46)
SCHEMBL17540392 0.73 ALDH1A1 (0.47) SOS1
SCHEMBL28040368 0.71 RAPGEF4 (0.30)
SCHEMBL11415517 0.69 CYP3A4 (0.35) SOS1
SCHEMBL16957136 0.69 TP53 (0.39)
SCHEMBL16957133 0.69
SCHEMBL518461 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed
WO-2008147480-A2 HYDROXAMIC ACID DERIVATIVES OF 3-PHENYL PROPIONIC ACIDS USEFUL AS THRAPEUTIC AGENTS FOR TREATING ANTHRAX POISONING PANTHERA BIOPHARNA, LLC. (US) 2008-12-04 WO disclosed