Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 11/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714171 | 0.86 | CETP (0.49) | CETP | |
| SCHEMBL7931627 | 0.81 | CETP (0.49) | CETPLTA4HFFAR1 | |
| SCHEMBL409247 | 0.81 | FFAR1 (0.51) | CETPLTA4HFFAR1ACACBACACA | |
| SCHEMBL9561406 | 0.81 | FFAR1 (0.51) | CETPLTA4HFFAR1ACACBACACA | |
| SCHEMBL9714593 | 0.80 | LTA4H (0.41) | CETPLTA4HFFAR1ACACBCNR2 | |
| SCHEMBL10865859 | 0.78 | LTA4H (0.45) | CETPLTA4HFFAR1NPC1CYP1A2 | |
| SCHEMBL9714624 | 0.78 | LTA4H (0.47) | CETPLTA4HFFAR1NPC1CYP1A2 | |
| SCHEMBL8613003 | 0.77 | LTA4H (0.51) | CETPLTA4HFFAR1ACACBACACA | |
| SCHEMBL10554911 | 0.77 | LTA4H (0.51) | CETPLTA4HFFAR1MGLLNPC1 | |
| SCHEMBL9714388 | 0.76 | LTA4H (0.45) | CETPLTA4HFFAR1NPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273549-B1 | INSECTICIDAL THIOETHERS AND DERIVATIVES THEREOF | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-02 | — | — | EP | disclosed |
| US-5068461-A | 1,1,1-trifluoro-2-(4-alkoxyphenyl)prop-2-ene compounds for aphids, mites and other insects | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-11-26 | — | — | US | disclosed |
| US-4937388-A | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-26 | — | — | US | disclosed |
| EP-0273549-A1 | Insecticidal thioethers and derivatives thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-07-06 | — | — | EP | disclosed |