Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6176132 | 0.89 | KDM4E (0.65) | ACHEKDM4EGAAMAPK1ROCK2 | |
| SCHEMBL6153702 | 0.84 | KDM4E (0.65) | ACHEKDM4EGAAMAPK1BCHE | |
| SCHEMBL13003296 | 0.81 | ACHE (0.71) | ACHEKDM4EGAAMAPK1BCHE | |
| SCHEMBL5671677 | 0.79 | KDM4E (0.70) | ACHEKDM4EGAAMAPK1ROCK2 | |
| SCHEMBL7289451 | 0.79 | KDM4E (0.70) | ACHEKDM4EGAAMAPK1ROCK2 | |
| SCHEMBL28332709 | 0.79 | KDM4E (0.70) | ACHEKDM4EGAAMAPK1ROCK2 | |
| SCHEMBL24074639 | 0.79 | KMT2A (0.47) | ACHEKDM4EGAAMAPT | |
| SCHEMBL5830478 | 0.79 | KDM4E (0.69) | ACHEKDM4EGAAMAPK1BCHE | |
| SCHEMBL4237535 | 0.78 | THRB (0.65) | ACHEKDM4EGAAROCK2ROCK1 | |
| SCHEMBL6154441 | 0.78 | ACHE (0.57) | ACHEKDM4EGAABCHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257583-B1 | PROCESS FOR ORTHO-CYANATION OF PHENOLS OR PHENYLAMINES | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4774331-A | THIOCYANATION IN PRESENCE OF BORON TRIFLUORIDE | SHIONOGI & CO., LTD. (JP) | 1988-09-27 | — | — | US | disclosed |
| EP-0257583-A1 | Process for ortho-cyanation of phenols or phenylamines | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |