Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.57 |
| ▸ | NSD2 | O96028 | 5/20 | 0.55 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154073 | 0.80 | DRD4 (0.58) | ACHEEZH2POLBTSHRDRD2 | |
| SCHEMBL8487979 | 0.78 | ACHE (0.69) | ACHENSD2EZH2BCHEBACE1 | |
| SCHEMBL9714210 | 0.78 | ACHE (0.67) | ACHEBCHEBACE1GAAALDH1A1 | |
| SCHEMBL6153702 | 0.76 | KDM4E (0.65) | ACHEBCHEBACE1GAAKDM4E | |
| SCHEMBL7289451 | 0.74 | KDM4E (0.70) | ACHEBCHEBACE1POLBGAA | |
| SCHEMBL6176132 | 0.73 | KDM4E (0.65) | ACHEBCHEBACE1GAAKDM4E | |
| SCHEMBL6153323 | 0.73 | SIGMAR1 (0.60) | EZH2GAATSHRALDH1A1HSD17B10 | |
| SCHEMBL9785772 | 0.73 | ACHE (0.71) | ACHENSD2EZH2BCHEBACE1 | |
| SCHEMBL23744610 | 0.73 | CHRM2 (0.70) | SIGMAR1 | |
| SCHEMBL14180586 | 0.73 | ACHE (0.57) | ACHENSD2EZH2BCHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1500643-A1 | BENZAMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | ACHE 3888/4885NSD2 2185/4885EZH2 1787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.