Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.61 |
| ▸ | PPARA | Q07869 | 2/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6328945 | 0.93 | HPGD (0.60) | LTA4HMAPTRAB9AMEN1HPGD | |
| Methylamine SCHEMBL6594130 | 0.90 | ALDH1A1 (0.58) | LTA4HMAPTRAB9AMEN1HPGD | |
| SCHEMBL6335494 | 0.88 | HDAC1 (0.63) | LTA4HPPARAMAPTRAB9AMEN1 | |
| SCHEMBL7364711 | 0.87 | HDAC3 (0.65) | LTA4HPPARAFFAR4FFAR1HDAC1 | |
| SCHEMBL25270797 | 0.87 | HDAC1 (0.66) | LTA4HMAPTRAB9AMEN1HPGD | |
| SCHEMBL10944790 | 0.87 | HDAC1 (0.66) | LTA4HMAPTRAB9AMEN1HPGD | |
| SCHEMBL839640 | 0.87 | HDAC1 (0.66) | LTA4HMAPTRAB9AMEN1HPGD | |
| Ethane SCHEMBL5322688 | 0.85 | HDAC1 (0.64) | LTA4HMAPTRAB9AMEN1HPGD | |
| SCHEMBL1811389 | 0.84 | RAB9A (0.59) | LTA4HMAPTRAB9AMEN1HPGD | |
| SCHEMBL8955656 | 0.84 | LTA4H (0.60) | LTA4HPPARAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246713-B1 | INTERMEDIATES FOR THE PRODUCTION OF NITROGEN-CONTAINING SUBSTITUTED HETEROCYCLIC COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-03-04 | — | — | EP | claimed |