Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714621 | 0.96 | KCNA3 (0.40) | BACE1KCNA3GAAESR1ESRRG | |
| SCHEMBL9714805 | 0.85 | GUSB (0.38) | — | |
| SCHEMBL1046791 | 0.82 | LTA4H (0.53) | LTA4HL3MBTL1 | |
| SCHEMBL9714791 | 0.82 | LTA4H (0.36) | MAOBLTA4HL3MBTL1 | |
| SCHEMBL7501215 | 0.77 | KCNA3 (0.62) | BACE1KCNA3GAALTA4H | |
| SCHEMBL25297779 | 0.76 | LMNA (0.53) | GAAMAOBLTA4HL3MBTL1FFAR1 | |
| SCHEMBL3156508 | 0.76 | LTA4H (0.50) | LTA4HL3MBTL1 | |
| SCHEMBL9714610 | 0.76 | MAOB (0.46) | GAAMAOBL3MBTL1 | |
| SCHEMBL9714604 | 0.76 | TDP1 (0.43) | ESR1MAOBL3MBTL1 | |
| SCHEMBL8616998 | 0.75 | KCNA3 (0.67) | KCNA3LTA4HL3MBTL1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166210-A | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5028615-A | Treatment of hypersensitivity | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-07-02 | — | — | US | disclosed |