Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 6/20 | 0.46 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL7049072 | 0.85 | TSHR (0.54) | TSHRTHRBCES1CES2MEN1 | |
| Heptane SCHEMBL502780 | 0.81 | TSHR (0.61) | TSHRTHRBCES1CES2MEN1 | |
| Decane SCHEMBL27152672 | 0.81 | TSHR (0.61) | TSHRTHRBCES1CES2MEN1 | |
| Hexane SCHEMBL20877590 | 0.81 | TSHR (0.58) | FAAHTSHRTHRBCES1CES2 | |
| Hexane SCHEMBL28293459 | 0.80 | FAAH (0.44) | FAAHTSHRTHRBCES1CES2 | |
| SCHEMBL29084332 | 0.80 | CES2 (0.50) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL15201721 | 0.80 | CES2 (0.50) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL15201847 | 0.80 | CES2 (0.50) | FAAHCES1CES2MEN1KMT2A | |
| Hexane SCHEMBL28858797 | 0.79 | SMN1; SMN2 (0.53) | TSHRTHRBMEN1KMT2AHSD17B10 | |
| SCHEMBL7779410 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4213321-A | — | — | None | — | — | JP | disclosed |
| EP-2964635-B1 | ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2018-05-02 | — | — | EP | disclosed |
| US-9693997-B2 | Antiviral compounds | HOFFMANN-LA ROCHE INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20160000760-A1 | ANTIVIRAL COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2016-01-07 | — | — | US | disclosed |
| JP-H04213321-A | SUTURE, POLYALKYLENE CARBONATE FOR COATING AND BIO-ABSORBABLE COPOLYMER OF RHO-DIOXANONE | ETHICON INC | 1992-08-04 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160000760-A1 | ANTIVIRAL COMPOUNDS | HAVCR2, EIF2AK2, MAVS | FAAH 2969/4885TSHR 4602/4885THRB 4622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.