SCHEMBL9714688

SCHEMBL9714688

CCCCOC(OCCCC)C(Cl)(Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36
ADRB3 P13945 1/20 0.36
DNM1 Q05193 1/20 0.35
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9714428 0.93 DNM1 (0.43) DNM1TSHRALDH1A1CA1CA2
SCHEMBL9714467 0.91 DNM1 (0.47) DNM1TSHRALDH1A1
SCHEMBL9714381 0.91 DNM1 (0.47) DNM1TSHRALDH1A1
SCHEMBL9714468 0.89 DNM1 (0.32) ADRB2ADRB1ADRB3DNM1
SCHEMBL11599959 0.81 DNM1 (0.33) ADRB2ADRB1ADRB3DNM1CYP3A4
SCHEMBL26564625 0.77 ADRB2 (0.38) ADRB2ADRB1ADRB3DNM1CYP3A4
SCHEMBL11281865 0.76 TSHR (0.34) ADRB2ADRB1ADRB3DNM1CYP3A4
SCHEMBL9714462 0.73 THRB (0.42)
SCHEMBL9648988 0.71 DNM1 (0.33) ADRB2ADRB1ADRB3DNM1CYP3A4
SCHEMBL11601955 0.71 DNM1 (0.33) ADRB2ADRB1ADRB3DNM1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4593978-A1 METHOD FOR DEPLETING PYRROLIZIDINE ALKALOIDS IN COMFREY ROOT EXTRACTS BY MEANS OF LIQUID-LIQUID CHROMATOGRAPHY RotaChrom Technológiai Zrt. (HU) 2025-08-06 EP disclosed
US-20250237650-A1 GLYCOSAMINOGLYCAN ARTICLES AND METHODS RELATING THERETO NATIONAL SCIENCE FOUNDATION 2025-07-24 US disclosed
CN-222921760-U Wing with embedded power module 厦门腾希航空科技有限公司 2025-05-30 CN disclosed
CN-119947808-A Method for reducing pyrrolizidine alkaloids in radix Arnebiae extract by liquid-liquid chromatography 罗塔赫罗姆技术股份公司 2025-05-06 CN disclosed
WO-2025038856-A1 METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING AUTOIMMUNE DISEASE NEW YORK UNIVERSITY (US) 2025-02-20 WO disclosed
US-20250000415-A1 METHOD AND SYTEM FOR PREDICTING NEURAL ACTIVATION AND PSYCHOPATHOLOGY IN SUBJECTS UNIVERSITY OF MASSACHUSETTS (US) 2025-01-02 US disclosed
CN-115209890-B Shikonin, arylnaphthalene lignans and pharmaceutical compositions containing them for inhibiting expression of pro-inflammatory genes 宝洁公司 2024-12-17 CN disclosed
CN-118877197-A Wing with embedded power module and aircraft 厦门腾希航空科技有限公司 2024-11-01 CN disclosed
US-20240247048-A1 VASOACTIVE INTESTINAL PEPTIDE (VIP) RECEPTOR ANTAGONISTS CAMBIUM ONCOLOGY LLC 2024-07-25 US disclosed
US-20240207219-A1 Artemisia anti-bacterial compositions and methods of use for inhibition of cells of Mycobacterium species NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-06-27 US disclosed
WO-2022245820-A1 VASOACTIVE INTESTINAL PEPTIDE (VIP) RECEPTOR ANTAGONISTS EMORY UNIVERSITY (US) 2022-11-24 WO disclosed
CN-115209890-A Alkannin and arylnaphthalene lignan for inhibiting expression of proinflammatory genes and pharmaceutical composition containing same 宝洁公司 2022-10-18 CN disclosed
EP-3871672-B1 COMFREYNS, ARYLNAPHTHALENE LIGNANS THAT INHIBIT PRO-INFLAMMATORY GENE EXPRESSION, AND PHARMACEUTICAL COMPOSITION COMPRISING THEM PROCTER & GAMBLE (US) 2022-08-17 EP disclosed
WO-2022164451-A1 COMPOSITIONS AND METHODS FOR TREATING CEREBROSPINAL FLUID DISORDERS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2022-08-04 WO disclosed
WO-2022152701-A1 COMBINATION THERAPY F. HOFFMANN-LA ROCHE AG (CH) 2022-07-21 WO disclosed
US-11389171-B2 Integrated system for the infixion and retrieval of implants GOLDSMITH DAVID S (US) 2022-07-19 US disclosed
US-20220122213-A1 ELECTRIC VEHICLE RESCUE SYSTEM IP VENUE, LLC 2022-04-21 US disclosed
US-5116402-A HERBICIDAL COMPOSITION CONTAINING DIOXOLANE, DIOXANE, OR DIOXEPANE DERIVATIVES AS ANTIDOTE MAGYAR TUDOMANVOS AKADEMIA KOZPONTI KEMIAI KUTATO INTEZETE NITROKEMIA INARTELENEK FUZFOGYARTELEP (HU) 1992-05-26 US disclosed
EP-0054278-B1 PLANT PROTECTING AGENTS FOR USE DURING WEED CONTROL, 2-(DICHLOROMETHYL)-3-PHENYL-1,3-OXAZOLIDINE AND 2-(DICHLOROMETHYL)-3-ALLYL-1,3-OXAZOLIDINE, AND METHOD FOR THE PREPARATION OF THE COMPOUNDS COMPRISED IN SAID AGENTS AS ANTIDOTES, OR OF THE LATTER MENTIONED COMPOUNDS MAGYAR TUDOMANYOS AKADEMIA KÖZP KEMIAI KUTATO INTEZET (HU) 1987-04-01 EP disclosed
EP-0054278-A1 Plant protecting agents for use during weed control, 2-(dichloromethyl)-3-phenyl-1,3-oxazolidine and 2-(dichloromethyl)-3-allyl-1,3-oxazolidine, and method for the preparation of the compounds comprised in said agents as antidotes, or of the latter mentioned compounds MAGYAR TUDOMANYOS AKADEMIA KÖZP KEMIAI KUTATO INTEZET (HU) 1982-06-23 EP disclosed