3,4-Dimethylphenylmaleimide

3,4-Dimethylphenylmaleimide

SCHEMBL9714890

CC1=C(C)C(=O)N(c2ccccc2)C1=O.CC1=CC(=O)N(c2ccccc2)C1=O.CCC1=C(CC)C(=O)N(c2ccccc2)C1=O.CCC1=CC(=O)N(c2ccccc2)C1=O

nearest known ligand 0.37

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.33
RAB9A P51151 2/20 0.33
PARP1 P09874 1/20 0.33
PARP15 Q460N3 1/20 0.33
PARP10 Q53GL7 1/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 3/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
CASP1 P29466 1/20 0.32
CASP3 P42574 1/20 0.32
CASP7 P55210 1/20 0.32
SENP8 Q96LD8 1/20 0.32
HSD17B10 Q99714 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
MGLL Q99685 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3444955 0.82 ELANE (0.46) ELANERAB9AMEN1GAAKMT2A
SCHEMBL774452 0.78 MGLL (0.50) ELANEMEN1GAAKMT2AALDH1A1
SCHEMBL29778344 0.77 MGLL (0.42) ELANEMEN1KMT2AALDH1A1MGLL
SCHEMBL550965 0.76 ELANE (0.52) ELANERAB9AMEN1GAAKMT2A
Benzene SCHEMBL11339098 0.73 MGLL (0.45) ELANERAB9AMEN1GAAKMT2A
SCHEMBL94147 0.72 MGLL (0.46) ELANERAB9AMEN1KMT2AMGLL
SCHEMBL30309847 0.72 MGLL (0.56) ELANEGAAALDH1A1MGLLNPSR1
3,4-Dimethylphenylmaleimide SCHEMBL5074358 0.71 PARP1 (0.53) ELANEPARP1PARP15PARP10GAA
SCHEMBL9276702 0.70 MGLL (0.52) RAB9AMEN1KMT2AALDH1A1KDM4E
SCHEMBL9177459 0.70 FAAH (0.41) MEN1GAAKMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0493811-A2 Improved thermoplastic resin composition and method for producing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-07-08 EP disclosed