Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715018 | 0.87 | TDP1 (0.47) | L3MBTL1ALDH1A1HTTHPGDKDM4E | |
| SCHEMBL9714993 | 0.85 | KMT2A (0.47) | L3MBTL1ALDH1A1HTTLMNAMDM2 | |
| SCHEMBL11471490 | 0.85 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1HTTHPGDKDM4E | |
| SCHEMBL10403783 | 0.82 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1HTTHPGDKDM4E | |
| SCHEMBL10594726 | 0.81 | HTT (0.47) | L3MBTL1ALDH1A1HTTHPGDKDM4E | |
| SCHEMBL1360295 | 0.81 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1HTTHPGDKDM4E | |
| SCHEMBL11235282 | 0.79 | CYP2C9 (0.49) | L3MBTL1ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL26282473 | 0.77 | NTSR1 (0.52) | L3MBTL1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL8381296 | 0.76 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1HTTLMNAMAPT | |
| SCHEMBL5212344 | 0.75 | MDM2 (0.45) | L3MBTL1ALDH1A1HTTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018484-A1 | 3-AMINO-5-ARYLPYRAZOLE-4-ACETIC ACID DERIVATIVES EXHIBITING THERAPEUTIC EFFECTS | A.H. ROBINS COMPANY, INCORPORATED (US) | 1992-10-29 | — | — | WO | disclosed |
| US-5057534-A | Anxiolytic, anticonfulsant and muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |