Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.69 |
| ▸ | ECE1 | P42892 | 11/20 | 0.62 |
| ▸ | MME | P08473 | 10/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715281 | 0.91 | ACE2 (0.62) | ACE2ECE1MME | |
| SCHEMBL9697199 | 0.90 | ACE2 (0.70) | ACE2ECE1MME | |
| SCHEMBL9698581 | 0.87 | ACE2 (0.58) | ACE2ECE1MME | |
| SCHEMBL9715090 | 0.85 | MMP8 (0.64) | ACE2ECE1MME | |
| SCHEMBL6929734 | 0.85 | ACE2 (0.73) | ACE2ECE1MMEHSD17B10 | |
| SCHEMBL9715088 | 0.85 | ECE1 (0.60) | ACE2ECE1MME | |
| SCHEMBL7283423 | 0.85 | ACE2 (0.60) | ACE2ECE1MMEHSD17B10 | |
| SCHEMBL6924717 | 0.84 | ACE2 (0.84) | ACE2ECE1MME | |
| SCHEMBL6928745 | 0.83 | ECE1 (0.77) | ACE2ECE1MME | |
| SCHEMBL9697698 | 0.82 | ECE1 (0.55) | ACE2ECE1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143908-A | Carboxylic acids containing amino and phosphinyl groups | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| US-4715994-A | PHOSPHINIC ACID DERIVATIVES | MERCK & CO., INC. (US) | 1987-12-29 | — | — | US | disclosed |