Acifluorfen

Acifluorfen

SCHEMBL9715148

C=CC=O.C=CC=O.Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl.Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl.O=C(O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].O=C(O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.71

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.71
MEN1 O00255 2/20 0.71
TTR P02766 2/20 0.71
KMT2A Q03164 2/20 0.71
PPOX P50336 1/20 0.71
ALB P02768 1/20 0.53
THRB P10828 1/20 0.53
FFAR1 O14842 4/20 0.42
AKR1B1 P15121 1/20 0.42
AKR1C4 P17516 1/20 0.42
AKR1C3 P42330 1/20 0.42
AKR1C2 P52895 1/20 0.42
AKR1C1 Q04828 1/20 0.42
PYGL P06737 1/20 0.41
MAPT P10636 3/20 0.40
LMNA P02545 2/20 0.40
POLB P06746 1/20 0.40
CCR6 P51684 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
GPR55 Q9Y2T6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acifluorfen SCHEMBL9738897 0.95 TDP1 (0.79) TDP1MEN1TTRKMT2APPOX
Acifluorfen SCHEMBL7577847 0.95 TDP1 (0.79) TDP1MEN1TTRKMT2APPOX
Acifluorfen SCHEMBL9698657 0.91 TDP1 (0.86) TDP1MEN1TTRKMT2APPOX
Acifluorfen SCHEMBL7578063 0.86 TDP1 (0.62) TDP1MEN1TTRKMT2APPOX
Acifluorfen SCHEMBL29445767 0.84 TDP1 (1.00) TDP1MEN1TTRKMT2APPOX
Acifluorfen SCHEMBL8028079 0.84 TDP1 (1.00) TDP1MEN1TTRKMT2APPOX
Acifluorfen SCHEMBL29448829 0.84 TDP1 (1.00) TDP1MEN1TTRKMT2APPOX
Acifluorfen SCHEMBL38929 0.84 TDP1 (1.00) TDP1MEN1TTRKMT2APPOX
Acifluorfen SCHEMBL3228873 0.84 TDP1 (1.00) TDP1MEN1TTRKMT2APPOX
Acifluorfen SCHEMBL9539519 0.83 TDP1 (0.49) TDP1MEN1TTRKMT2APPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992009578-A1 SUBSTITUTED FUSED HETEROCYCLIC HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-11 WO disclosed