Acifluorfen

Acifluorfen

SCHEMBL7577847

Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl.O=C(O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.79
MEN1 O00255 2/20 0.79
TTR P02766 2/20 0.79
KMT2A Q03164 2/20 0.79
PPOX P50336 1/20 0.79
ALB P02768 1/20 0.59
THRB P10828 1/20 0.59
FFAR1 O14842 5/20 0.46
AKR1B1 P15121 1/20 0.46
AKR1C4 P17516 1/20 0.46
AKR1C3 P42330 1/20 0.46
AKR1C2 P52895 1/20 0.46
AKR1C1 Q04828 1/20 0.46
PYGL P06737 1/20 0.44
MAPT P10636 3/20 0.43
LMNA P02545 2/20 0.43
POLB P06746 1/20 0.43
CCR6 P51684 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
GPR55 Q9Y2T6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acifluorfen SCHEMBL9738897 1.00 TDP1 (0.79) TDP1MEN1TTRKMT2APPOX
Acifluorfen SCHEMBL9715148 0.95 TDP1 (0.71) TDP1MEN1TTRKMT2APPOX
Acifluorfen SCHEMBL7578063 0.89 TDP1 (0.62) TDP1MEN1TTRKMT2APPOX
Acifluorfen SCHEMBL38929 0.89 TDP1 (1.00) TDP1MEN1TTRKMT2APPOX
Acifluorfen SCHEMBL8028079 0.89 TDP1 (1.00) TDP1MEN1TTRKMT2APPOX
Acifluorfen SCHEMBL29445767 0.89 TDP1 (1.00) TDP1MEN1TTRKMT2APPOX
Acifluorfen SCHEMBL29448829 0.89 TDP1 (1.00) TDP1MEN1TTRKMT2APPOX
Acifluorfen SCHEMBL3228873 0.89 TDP1 (1.00) TDP1MEN1TTRKMT2APPOX
Acifluorfen SCHEMBL1830812 0.88 TDP1 (0.98) TDP1MEN1TTRKMT2APPOX
Acifluorfen SCHEMBL10556004 0.88 TDP1 (0.98) TDP1MEN1TTRKMT2APPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.