Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12579271 | 0.91 | MAPT (0.49) | SMN1; SMN2HSD17B10ALDH1A1KDM4ETP53 | |
| SCHEMBL15977734 | 0.88 | KDM4E (0.47) | SMN1; SMN2HSD17B10ALDH1A1KDM4ETP53 | |
| SCHEMBL15977456 | 0.88 | KDM4E (0.49) | SMN1; SMN2HSD17B10ALDH1A1KDM4ETP53 | |
| SCHEMBL24662785 | 0.87 | KDM4E (0.55) | SMN1; SMN2HSD17B10ALDH1A1KDM4ETP53 | |
| SCHEMBL18334154 | 0.87 | CCR1 (0.45) | SMN1; SMN2HSD17B10ALDH1A1KDM4ETP53 | |
| SCHEMBL973879 | 0.86 | CYP1A1 (0.55) | SMN1; SMN2HSD17B10ALDH1A1KDM4ETP53 | |
| SCHEMBL17013900 | 0.86 | ALDH1A1 (0.47) | SMN1; SMN2HSD17B10ALDH1A1KDM4ETP53 | |
| SCHEMBL13154553 | 0.85 | KDM4E (0.55) | SMN1; SMN2HSD17B10ALDH1A1KDM4ETP53 | |
| SCHEMBL972054 | 0.85 | CCR1 (0.51) | SMN1; SMN2HSD17B10ALDH1A1KDM4ETP53 | |
| SCHEMBL973168 | 0.85 | ADORA3 (0.49) | SMN1; SMN2HSD17B10ALDH1A1KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7867629-B2 | Nitrogenous heterocyclic derivative and organic electroluminescent element employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-01-11 | — | — | US | disclosed |
| US-20060154105-A1 | Nitrogenous heterocyclic derivative and organic elecrtroluminescent element employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2006-07-13 | — | — | US | disclosed |
| EP-1582516-A1 | NITROGENOUS HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2005-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154105-A1 | Nitrogenous heterocyclic derivative and organic elecrtroluminescent element employing the same | L1CAM, NOTCH1, NUDC | SMN1; SMN2 1021/4885HSD17B10 3837/4885ALDH1A1 325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.