Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.49 |
| ▸ | CCR1 | P32246 | 3/20 | 0.47 |
| ▸ | CCR5 | P51681 | 3/20 | 0.47 |
| ▸ | CCR8 | P51685 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | METAP1 | P53582 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12579263 | 0.88 | DHODH (0.48) | ADORA3CCR1CCR5CCR8SMN1; SMN2 | |
| SCHEMBL10051240 | 0.87 | DHODH (0.47) | ADORA3CCR1CCR5CCR8SMN1; SMN2 | |
| SCHEMBL971862 | 0.85 | CCR1 (0.45) | ADORA3CCR1CCR5CCR8SMN1; SMN2 | |
| SCHEMBL28190882 | 0.85 | KDM4E (0.58) | CCR1CCR5CCR8SMN1; SMN2NPC1 | |
| SCHEMBL971571 | 0.85 | MAPK1 (0.48) | ADORA3CCR1CCR5CCR8SMN1; SMN2 | |
| SCHEMBL971520 | 0.85 | SMN1; SMN2 (0.48) | ADORA3CCR1CCR5CCR8SMN1; SMN2 | |
| SCHEMBL971280 | 0.84 | MEN1 (0.55) | ADORA3SMN1; SMN2LMNAKDM4EMAPK1 | |
| SCHEMBL6551807 | 0.83 | KDM4E (0.54) | ADORA3CCR1CCR5CCR8SMN1; SMN2 | |
| SCHEMBL22766675 | 0.82 | KDM4E (0.43) | ADORA3CCR1CCR5CCR8SMN1; SMN2 | |
| SCHEMBL18698104 | 0.82 | MEN1 (0.56) | CCR1CCR5CCR8SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7867629-B2 | Nitrogenous heterocyclic derivative and organic electroluminescent element employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-01-11 | — | — | US | disclosed |
| US-20060154105-A1 | Nitrogenous heterocyclic derivative and organic elecrtroluminescent element employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2006-07-13 | — | — | US | disclosed |
| EP-1582516-A1 | NITROGENOUS HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2005-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154105-A1 | Nitrogenous heterocyclic derivative and organic elecrtroluminescent element employing the same | L1CAM, NOTCH1, NUDC | ADORA3 3036/4885CCR1 4435/4885CCR5 4004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.