Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 6/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5968850 | 0.79 | ESR2 (0.56) | ESR2ESR1SLC6A4SLC6A3KDM4E | |
| SCHEMBL21051570 | 0.72 | ESR2 (0.56) | ESR2ESR1DRD2DRD4DRD3 | |
| SCHEMBL14575804 | 0.71 | ESR2 (0.37) | ESR2ESR1 | |
| SCHEMBL6058583 | 0.70 | ESR1 (0.64) | ESR2ESR1SLC6A4SLC6A3DRD2 | |
| SCHEMBL19615271 | 0.67 | ESR2 (0.45) | ESR2ESR1DRD2DRD4DRD3 | |
| SCHEMBL3035977 | 0.67 | ESR2 (0.45) | ESR2ESR1KDM4EMEN1NPC1 | |
| SCHEMBL652586 | 0.67 | DRD2 (0.68) | ESR2ESR1DRD2DRD4DRD3 | |
| SCHEMBL18244775 | 0.67 | OPRM1 (0.53) | SLC6A4SLC6A3DRD2DRD4DRD3 | |
| SCHEMBL7737678 | 0.66 | OPRM1 (0.42) | SLC6A4SLC6A3DRD2DRD4DRD3 | |
| SCHEMBL22411503 | 0.66 | DRD2 (0.45) | ESR2ESR1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287290-B1 | PREPARATION PROCESS OF 4,4'-BIPHENOL, PRECURSOR OF SAME AND PREPARATION PROCESS OF PRECURSOR | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-07-08 | — | — | EP | claimed |
| EP-0287290-A1 | Preparation process of 4,4'-biphenol, precursor of same and preparation process of precursor | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-10-19 | — | — | EP | claimed |
| US-4894487-A | Preparation process of 4-(4-hydroxyphenyl)-cyclohexanol | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1990-01-16 | — | — | US | disclosed |