Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6397498 | 0.81 | EEF2K (0.47) | EEF2KMEN1KMT2ALMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL11780574 | 0.80 | EEF2K (0.62) | EEF2KMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11780426 | 0.78 | EEF2K (0.95) | EEF2KMEN1KMT2ATP53MAPK1 | |
| Hydrochloric Acid SCHEMBL11786436 | 0.78 | EEF2K (0.59) | EEF2KMEN1KMT2AMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7775450 | 0.78 | EEF2K (0.59) | EEF2KMEN1KMT2AMAPK1SMN1; SMN2 | |
| Water SCHEMBL11786512 | 0.77 | EEF2K (0.62) | EEF2KMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7776941 | 0.76 | EEF2K (0.61) | EEF2KMEN1KMT2AMAPK1SMN1; SMN2 | |
| Bromide SCHEMBL11783733 | 0.76 | EEF2K (0.95) | EEF2KMEN1KMT2ATP53MAPK1 | |
| Hydrochloric Acid SCHEMBL11784271 | 0.74 | EEF2K (0.43) | EEF2KHTT | |
| Hydrochloric Acid SCHEMBL11783365 | 0.73 | EEF2K (0.51) | EEF2KMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500712-A1 | COMBATTING SLIME-FORMING MICROORGANISMS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1992-09-02 | — | — | EP | disclosed |
| WO-1991007090-A1 | COMBATTING SLIME-FORMING MICROORGANISMS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1991-05-30 | — | — | WO | disclosed |
| US-3931129-A | FLUOROELASTOMER COMPOSITION | DAIKIN KOGYO CO., LTD. (JA) | 1976-01-06 | — | — | US | disclosed |