Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL11786512 | 0.83 | EEF2K (0.62) | EEF2KKMT2APOLBMEN1LMNA | |
| Hydrochloric Acid SCHEMBL11780574 | 0.83 | EEF2K (0.62) | EEF2KKMT2APOLBMEN1LMNA | |
| Hydrochloric Acid SCHEMBL9715398 | 0.81 | EEF2K (0.61) | EEF2KKMT2APOLBMEN1LMNA | |
| SCHEMBL1834262 | 0.77 | POLB (0.44) | EEF2KKMT2APOLBKDM4EMEN1 | |
| SCHEMBL28946773 | 0.66 | POLB (0.50) | KMT2APOLBMEN1LMNASIGMAR1 | |
| SCHEMBL4084447 | 0.64 | LMNA (0.48) | KMT2APOLBMEN1LMNASIGMAR1 | |
| SCHEMBL21049606 | 0.64 | BRD4 (0.43) | KMT2APOLBKDM4EMEN1LMNA | |
| SCHEMBL16786536 | 0.63 | SIGMAR1 (0.58) | KMT2APOLBMEN1LMNASIGMAR1 | |
| Hydrochloric Acid SCHEMBL4081730 | 0.63 | LMNA (0.47) | KMT2APOLBKDM4EMEN1LMNA | |
| SCHEMBL27883631 | 0.62 | POLB (0.47) | KMT2APOLBMEN1LMNASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6977246-B2 | Certain dinucleotides and their use as modulators of mucociliary clearance and ciliary beat frequency | INSPIRE PHARMACEUTICALS, INC. (US) | 2005-12-20 | — | — | US | disclosed |
| US-20050272936-A1 | Imidazolium cxcr3 inhibitors | SMITHKLINE BEECHAM CORPORATION | 2005-12-08 | — | — | US | disclosed |
| US-6348589-B1 | INCREASE THE HYDRATION OF RETAINED MUCUS SECRETIONS, STIMULATE THE PRODUCTION OF MUCINS; TREATING CHRONIC BRONCHITIS, CYSTIC FIBROSIS AND PNEUMONIA | INSPIRE PHARMACEUTICALS, INC. | 2002-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272936-A1 | Imidazolium cxcr3 inhibitors | CXCR3, CXCR1, CCR7 | EEF2K 4542/4885KMT2A 4040/4885POLB 3275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.