Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30149971 | 0.87 | CD44 (0.36) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL30149972 | 0.87 | CD44 (0.36) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL6228555 | 0.85 | TDP1 (0.36) | CYP3A4ALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL6226289 | 0.85 | MAPK13 (0.35) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL7220722 | 0.81 | PTGS1 (0.40) | SMN1; SMN2ALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL23020250 | 0.80 | CYP3A4 (0.35) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL43388 | 0.78 | ALDH1A1 (0.42) | CYP3A4ALOX15ALDH1A1MAPTKDM4E | |
| SCHEMBL5516786 | 0.78 | ALDH1A1 (0.42) | CYP3A4ALOX15ALDH1A1MAPTKDM4E | |
| SCHEMBL890760 | 0.77 | NOS3 (0.35) | SMN1; SMN2ALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL22879338 | 0.76 | ALDH1A1 (0.39) | CYP3A4ALOX15ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304402-B1 | ANILINOPHENYL THIOUREAS, ISOTHIOUREAS AND CARBODIIMIDES, THEIR PREPARATION AND THEIR USE IN PEST-CONTROL | CIBA-GEIGY AG (CH) | 1992-05-06 | — | — | EP | disclosed |
| EP-0304402-A2 | Anilinophenyl thioureas, isothioureas and carbodiimides, their preparation and their use in pest-control | CIBA-GEIGY AG (CH) | 1989-02-22 | — | — | EP | disclosed |