Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906154 | 0.84 | PTGS1 (0.37) | PTGS1KIF11ALDH1A1TSHRNSD2 | |
| SCHEMBL9715426 | 0.81 | CYP3A4 (0.35) | ALDH1A1TSHRMAPTLMNAGAA | |
| SCHEMBL6226289 | 0.79 | MAPK13 (0.35) | ALDH1A1TSHRMAPTLMNAGAA | |
| SCHEMBL6228555 | 0.79 | TDP1 (0.36) | ALDH1A1TSHRMAPTGAAKDM4E | |
| SCHEMBL30149972 | 0.70 | CD44 (0.36) | ALDH1A1TSHRMAPTLMNAGAA | |
| SCHEMBL30149971 | 0.70 | CD44 (0.36) | ALDH1A1TSHRMAPTLMNAGAA | |
| SCHEMBL10589464 | 0.69 | KIF11 (0.43) | KIF11ALDH1A1TSHR | |
| SCHEMBL890760 | 0.68 | NOS3 (0.35) | ALDH1A1TSHRMAPTHDAC2KDM4E | |
| SCHEMBL7214602 | 0.68 | PTPN1 (0.47) | ALDH1A1TSHRMAPTLMNAGAA | |
| SCHEMBL6903434 | 0.66 | ALDH1A1 (0.48) | ALDH1A1TSHRLMNAGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6548548-B2 | ABCA-1 elevating compounds | CV THERAPEUTICS, INC. | 2003-04-15 | — | — | US | disclosed |
| US-20020111364-A1 | ABCA-1 elevating compounds | CV THERAPEUTICS, INC. | 2002-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111364-A1 | ABCA-1 elevating compounds | ABCD3, ABCE1, ABCB4 | PTGS1 1408/4885KIF11 4183/4885ALDH1A1 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.