SCHEMBL9715762

SCHEMBL9715762

CCOC1(C=CC=Cc2ccccc2)C=CC=CC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.37
LMNA P02545 4/20 0.35
RAB9A P51151 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 2/20 0.35
RELA Q04206 1/20 0.35
ALDH1A1 P00352 6/20 0.33
TRPA1 O75762 1/20 0.33
ALOX5 P09917 1/20 0.33
MAPK1 P28482 1/20 0.33
KDM4E B2RXH2 5/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
ADORA3 P0DMS8 1/20 0.32
XBP1 P17861 1/20 0.32
CTDSP1 Q9GZU7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9715775 0.85 MAOB (0.40) MAOBLMNARELAALDH1A1TRPA1
SCHEMBL9715739 0.78 MAOB (0.41) MAOBLMNARAB9AL3MBTL1SMN1; SMN2
SCHEMBL9715726 0.75 RAB9A (0.43) LMNARAB9AL3MBTL1SMN1; SMN2NPC1
SCHEMBL9715750 0.69 HDAC3 (0.38) MAOBLMNARAB9AL3MBTL1SMN1; SMN2
SCHEMBL9715733 0.69 MAOB (0.40) MAOBLMNARAB9ASMN1; SMN2NPC1
SCHEMBL28754743 0.68 CHRNA7 (0.33) RELAALDH1A1KDM4EMEN1KMT2A
Hydrogen Sulfide SCHEMBL28261934 0.68
SCHEMBL9715711 0.67 FBP1 (0.38) MAOBLMNARAB9ANPC1ALDH1A1
SCHEMBL28136076 0.66 MAOB (0.37) MAOBLMNASMN1; SMN2ALDH1A1TRPA1
SCHEMBL11075469 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0311689-B1 PROCESS FOR SELECTIVELY MONOHYDROFORMYLATING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-06-10 EP disclosed
EP-0304495-B1 PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-05-27 EP disclosed
US-4982007-A CARBONYLATION CATALYST NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-01-01 US disclosed
US-4908473-A Reacting a (1-arylethenyl)vinylbenzene with carbon monoxide and water or alcohol in the presence of carbonylation catalyst NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1990-03-13 US disclosed
EP-0311689-A1 PROCESS FOR SELECTIVELY MONOHYDROFORMYLATING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-04-19 EP disclosed
EP-0304495-A1 PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-03-01 EP disclosed