Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1833359 | 0.82 | ACHE (0.60) | ACHEALDH1A1CYP3A4L3MBTL1KMT2A | |
| SCHEMBL30680643 | 0.79 | ACHE (0.52) | ACHEALDH1A1CYP3A4L3MBTL1KMT2A | |
| SCHEMBL2325597 | 0.79 | ACHE (0.52) | ACHEALDH1A1CYP3A4L3MBTL1KMT2A | |
| SCHEMBL9715789 | 0.77 | CA12 (0.60) | ALDH1A1CYP3A4L3MBTL1KMT2AGAA | |
| SCHEMBL29617571 | 0.76 | ALDH1A1 (0.45) | ALDH1A1CYP3A4L3MBTL1KMT2AMEN1 | |
| SCHEMBL16795954 | 0.76 | ALDH1A1 (0.45) | ALDH1A1CYP3A4L3MBTL1KMT2AMEN1 | |
| SCHEMBL29403877 | 0.75 | ACHE (1.00) | ACHEALDH1A1CYP3A4L3MBTL1KMT2A | |
| SCHEMBL12518 | 0.75 | ACHE (1.00) | ACHEALDH1A1CYP3A4L3MBTL1KMT2A | |
| SCHEMBL17529814 | 0.75 | ACHE (0.42) | ACHEALDH1A1CYP3A4L3MBTL1KMT2A | |
| SCHEMBL17529679 | 0.75 | ACHE (0.42) | ACHEALDH1A1CYP3A4L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0286196-B1 | PREPARATION OF SUBSTITUTED DIARYL PHOSPHIDES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-03-25 | — | — | EP | disclosed |
| EP-0286196-A2 | Preparation of substituted diaryl phosphides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-10-12 | — | — | EP | disclosed |