SCHEMBL29617571

SCHEMBL29617571

COc1ccc(Cl)cc1P(c1cc(Cl)ccc1OC)c1cc(Cl)ccc1OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.45
HPGD P15428 3/20 0.45
HTR3E A5X5Y0 2/20 0.45
HTR3B O95264 2/20 0.45
HTR3A P46098 2/20 0.45
HTR3D Q70Z44 2/20 0.45
HTR3C Q8WXA8 2/20 0.45
TRPV4 Q9HBA0 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
TTR P02766 2/20 0.41
LMNA P02545 1/20 0.41
KDM4E B2RXH2 2/20 0.40
POLB P06746 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16795954 1.00 ALDH1A1 (0.45) ALDH1A1HPGDHTR3EHTR3BHTR3A
SCHEMBL18085326 0.91 ALDH1A1 (0.40) ALDH1A1HPGDHTR3EHTR3BHTR3A
SCHEMBL668348 0.83 TRPV4 (0.48) ALDH1A1HTR3EHTR3BHTR3AHTR3D
SCHEMBL29636402 0.77 TRPV4 (0.55) ALDH1A1HTR3EHTR3BHTR3AHTR3D
SCHEMBL2127233 0.77 TRPV4 (0.55) ALDH1A1HTR3EHTR3BHTR3AHTR3D
SCHEMBL9715823 0.76 ACHE (0.60) ALDH1A1HPGDMEN1KMT2ACYP3A4
SCHEMBL9715789 0.76 CA12 (0.60) ALDH1A1MEN1KMT2ACYP1A2CYP3A4
SCHEMBL10382796 0.75 ALDH1A1 (0.41) ALDH1A1HPGDMEN1KMT2ACYP2D6
SCHEMBL196490 0.75 TTR (0.62) ALDH1A1HPGDTRPV4MEN1KMT2A
SCHEMBL7699644 0.75 ALDH1A1 (0.56) ALDH1A1HPGDTRPV4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331643-A1 BUTADIENE TELOMERIZATION CATALYST PREPARATION AND USE THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2023-10-19 US disclosed
US-11713286-B2 Butadiene telomerization catalyst preparation and use thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2023-08-01 US disclosed
US-20220213006-A1 BUTADIENE TELOMERIZATION CATALYST PREPARATION AND USE THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2022-07-07 US disclosed
US-11312670-B2 Butadiene telomerization catalyst and preparation thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2022-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11312670-B2 Butadiene telomerization catalyst and preparation thereof TELO2, TERT, POT1 ALDH1A1 824/4885HPGD 1233/4885HTR3E 2370/4885
US-11713286-B2 Butadiene telomerization catalyst preparation and use thereof TELO2, TERT, TPR ALDH1A1 954/4885HPGD 1254/4885HTR3E 2291/4885
US-20230331643-A1 BUTADIENE TELOMERIZATION CATALYST PREPARATION AND USE THEREOF TELO2, TERT, TPR ALDH1A1 954/4885HPGD 1254/4885HTR3E 2291/4885
US-20220213006-A1 BUTADIENE TELOMERIZATION CATALYST PREPARATION AND USE THEREOF TELO2, TERT, TPR ALDH1A1 954/4885HPGD 1254/4885HTR3E 2291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.