Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CD74 | P04233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715954 | 0.83 | POLB (0.39) | IDO1POLBTSHRMAPK1HPGD | |
| SCHEMBL9715956 | 0.83 | IDO1 (0.38) | IDO1POLBTSHRMAPK1HPGD | |
| SCHEMBL9715982 | 0.83 | ALDH1A1 (0.43) | IDO1POLBTSHRMAPK1HPGD | |
| SCHEMBL9715971 | 0.80 | CYP2A6 (0.41) | POLBHPGDMIFCD74 | |
| SCHEMBL9715967 | 0.79 | MEN1 (0.36) | IDO1TSHRMAPK1HPGDUSP2 | |
| SCHEMBL9716043 | 0.78 | CYP2A6 (0.46) | POLBTSHRHPGDALDH1A1NPSR1 | |
| SCHEMBL9716001 | 0.77 | IDO1 (0.35) | IDO1POLBTSHRMAPK1HPGD | |
| SCHEMBL536696 | 0.76 | MAPK1 (0.62) | IDO1POLBTSHRMAPK1HPGD | |
| SCHEMBL18329422 | 0.74 | IDO1 (0.44) | IDO1HPGDALDH1A1 | |
| SCHEMBL29670897 | 0.74 | IDO1 (0.44) | IDO1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102898-A | Halosubstituted alkyne group; fungicides | ROHM AND HAAS COMPANY (US) | 1992-04-07 | — | — | US | disclosed |