SCHEMBL9715951

SCHEMBL9715951

O=c1oc2c(Br)cc(Br)cc2n1CC#CI

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 2/20 0.33
NPC1 O15118 1/20 0.33
NQO1 P15559 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9715955 0.80 ASAH1 (0.38)
SCHEMBL9715926 0.77 CBX7 (0.47) NPC1
SCHEMBL9715959 0.74 POLB (0.33)
SCHEMBL9715990 0.74 NPC1 (0.57) NPC1
SCHEMBL2149116 0.74 SIGMAR1 (0.39) GPR35NPC1NQO1
SCHEMBL9716001 0.69 IDO1 (0.35) NPC1
SCHEMBL31248706 0.68 MAOB (0.38) GPR35NQO1
SCHEMBL9716054 0.68 MIF (0.46)
SCHEMBL9716015 0.68 AHR (0.33)
SCHEMBL536696 0.67 MAPK1 (0.62)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5102898-A Halosubstituted alkyne group; fungicides ROHM AND HAAS COMPANY (US) 1992-04-07 US disclosed