SCHEMBL9716072

SCHEMBL9716072

CCO[Si](CC(C)c1ccccc1CCl)(OCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11846920 0.86 TSHR (0.32) TSHR
SCHEMBL11832647 0.84 NPBWR1 (0.32) TSHR
SCHEMBL27688026 0.79 ADRA2A (0.33)
SCHEMBL11832507 0.78 CYSLTR2 (0.31)
SCHEMBL11839515 0.78 TSHR (0.33) TSHR
SCHEMBL2526800 0.78 SLC6A2 (0.31) TSHR
SCHEMBL11845547 0.77 TSHR (0.32) TSHR
SCHEMBL11837296 0.77 TSHR (0.34) TSHR
SCHEMBL11841303 0.76 TSHR (0.32) TSHR
SCHEMBL8374306 0.73 TAAR1 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0477765-A2 Thermoplastic, coupled barrier composites THE B.F. GOODRICH COMPANY (US) 1992-04-01 EP disclosed
US-4146585-A COPOLYMER CONTAINING VINYL CHLORIDE AND HYDROXYALKYL ACRYLATE UNION CARBIDE CORPORATION (US) 1979-03-27 US disclosed
US-4113691-A PHENYLENE ETHER POLYMER UNION CARBIDE CORPORATION (US) 1978-09-12 US disclosed
US-3963726-A Quaternary ammonium salts of chloromethylated silicon compounds UNION CARBIDE CORPORATION (US) 1976-06-15 US disclosed