Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 12/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | GLA | P06280 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601296 | 1.00 | MIF (0.59) | MIFCA9TP53HSD17B3POLB | |
| SCHEMBL8143534 | 0.79 | SMN1; SMN2 (0.58) | CA9POLBKDM4EMEN1GAA | |
| SCHEMBL30488625 | 0.78 | GLA (0.62) | CA9POLBKDM4EMEN1GLA | |
| SCHEMBL1607327 | 0.77 | KDM4E (0.68) | MIFCA9TP53HSD17B3POLB | |
| SCHEMBL1861098 | 0.76 | HSD17B3 (0.60) | MIFCA9HSD17B3POLBESR2 | |
| SCHEMBL4818246 | 0.75 | TP53 (0.64) | MIFCA9TP53HSD17B3POLB | |
| SCHEMBL19877311 | 0.75 | TP53 (0.63) | MIFCA9TP53HSD17B3POLB | |
| SCHEMBL19877313 | 0.75 | TP53 (0.63) | MIFCA9TP53HSD17B3POLB | |
| SCHEMBL5296804 | 0.74 | HSD17B3 (0.68) | MIFCA9HSD17B3POLBESR2 | |
| SCHEMBL480127 | 0.74 | MIF (1.00) | MIFCA9HSD17B3POLBESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079144-A | Test For Antibiotic Sensitivity Or For Minimum Inhibitory Concentration Of The Antibiotic | RADIOMETER CORPORATE DEVELOPMENT LTD. (GB) | 1992-01-07 | — | — | US | disclosed |
| US-5064756-A | MICROBIAL SUSCEPTIBILITY ASSAY USING 7-N-(AMINOACYL)-7-AMIDO-4-METHYLCOUMARINS | SIEMENS HEALTHCARE DIAGNOSTICS INC. | 1991-11-12 | — | — | US | disclosed |
| EP-0091837-B1 | MICROBIOLOGICAL TEST PROCESSES AND APPARATUS | RADIOMETER CORPORATE DEVELOPMENT LIMITED (GB) | 1989-07-26 | — | — | EP | disclosed |