Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR known ✓ | P25105 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716338 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL9716349 | 0.86 | KMT2A (0.36) | PTAFR | |
| Hydrochloric Acid SCHEMBL9716371 | 0.85 | KMT2A (0.34) | PTAFR | |
| SCHEMBL9716400 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL9716418 | 0.78 | KMT2A (0.35) | PTAFR | |
| Hydrochloric Acid SCHEMBL9716365 | 0.77 | FDPS (0.31) | — | |
| Hydrochloric Acid SCHEMBL9716259 | 0.77 | KDM4A (0.33) | — | |
| Hydrochloric Acid SCHEMBL9716374 | 0.76 | GMNN (0.34) | PTAFR | |
| Hydrochloric Acid SCHEMBL9716386 | 0.76 | HTT (0.43) | — | |
| Hydrochloric Acid SCHEMBL10552441 | 0.75 | PTAFR (0.41) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5103007-A | Antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-07 | — | — | US | disclosed |