Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716240 | 0.97 | PLA2G2A (0.31) | PLA2G2ARECQLTSHRGLAHPGD | |
| SCHEMBL9716253 | 0.93 | PLA2G2A (0.31) | PLA2G2A | |
| SCHEMBL9716309 | 0.91 | — | — | |
| SCHEMBL9720198 | 0.86 | PLA2G2A (0.39) | PLA2G2ARECQLTSHRGLAHPGD | |
| SCHEMBL9716359 | 0.85 | HTT (0.35) | PLA2G2AUSP2 | |
| SCHEMBL9716228 | 0.84 | PLA2G2C (0.31) | PLA2G2APLA2G2C | |
| SCHEMBL9720221 | 0.84 | PLA2G2A (0.38) | PLA2G2ATSHRPLA2G2CKDM4EUSP2 | |
| SCHEMBL9720263 | 0.84 | PLA2G2A (0.38) | PLA2G2ATSHRPLA2G2CKDM4EUSP2 | |
| SCHEMBL9716222 | 0.83 | HTT (0.35) | PLA2G2APLA2G2CUSP2 | |
| SCHEMBL9716261 | 0.81 | MEN1 (0.40) | PLA2G2ATSHRMAPK1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5103007-A | Antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0378763-A1 | Lipids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-25 | — | — | EP | disclosed |