Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 5/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720221 | 1.00 | PLA2G2A (0.38) | PLA2G2APLA2G2CLPAR1LPAR3USP2 | |
| SCHEMBL9720198 | 0.95 | PLA2G2A (0.39) | PLA2G2APLA2G2CLPAR1LPAR3USP2 | |
| SCHEMBL9716384 | 0.90 | PLA2G2C (0.33) | PLA2G2APLA2G2CPLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL9716406 | 0.89 | TLR2 (0.33) | PLA2G2APLA2G2CTLR2 | |
| SCHEMBL9716310 | 0.88 | TLR2 (0.33) | PLA2G2ATLR2 | |
| SCHEMBL9716253 | 0.88 | PLA2G2A (0.31) | PLA2G2A | |
| SCHEMBL9716228 | 0.87 | PLA2G2C (0.31) | PLA2G2APLA2G2C | |
| SCHEMBL9716272 | 0.87 | PLA2G2C (0.33) | PLA2G2APLA2G2CUSP2KDM4EALDH1A1 | |
| SCHEMBL9716309 | 0.86 | — | — | |
| SCHEMBL9716274 | 0.86 | PLA2G2C (0.33) | PLA2G2APLA2G2CUSP2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081245-A | Selective antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| US-4920134-A | ANTITUMOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-24 | — | — | US | disclosed |
| EP-0356765-A2 | Carboxylic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-03-07 | — | — | EP | disclosed |
| EP-0302744-A2 | Glycerol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-08 | — | — | EP | disclosed |