Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 8/20 | 0.36 |
| ▸ | CA2 | P00918 | 8/20 | 0.36 |
| ▸ | CA9 | Q16790 | 7/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720221 | 0.95 | PLA2G2A (0.38) | PLA2G2ATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL9720263 | 0.95 | PLA2G2A (0.38) | PLA2G2ATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL9716272 | 0.89 | PLA2G2C (0.33) | PLA2G2ATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL9716274 | 0.88 | PLA2G2C (0.33) | PLA2G2ATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL9716258 | 0.86 | PLA2G2A (0.31) | PLA2G2ATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL9716384 | 0.85 | PLA2G2C (0.33) | PLA2G2APLA2G2C | |
| SCHEMBL9716240 | 0.85 | PLA2G2A (0.31) | PLA2G2ATSHRRECQLGLAHPGD | |
| SCHEMBL9716406 | 0.85 | TLR2 (0.33) | PLA2G2APLA2G2C | |
| SCHEMBL10516297 | 0.83 | PLA2G2A (0.35) | PLA2G2AKDM4EPLA2G2CLPAR1LPAR3 | |
| SCHEMBL9716310 | 0.83 | TLR2 (0.33) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081245-A | Selective antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0356765-A2 | Carboxylic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-03-07 | — | — | EP | disclosed |