Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 12/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 12/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | CDC42 | P60953 | 1/20 | 0.58 |
| ▸ | RAC1 | P63000 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9486872 | 1.00 | AKR1C3 (0.58) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL11743050 | 0.88 | MT-CO2 (0.47) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL9867902 | 0.85 | SLC6A4 (0.43) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL9867877 | 0.85 | SLC6A4 (0.43) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL9867894 | 0.85 | SLC6A4 (0.43) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL11805455 | 0.83 | AKR1C3 (0.58) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL11802747 | 0.83 | AKR1C3 (0.58) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL9116873 | 0.83 | AKR1C3 (0.58) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL4380166 | 0.83 | AKR1C3 (0.58) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL4380164 | 0.83 | AKR1C3 (0.58) | AKR1C3AKR1C2PTGS2PTGS1CDC42 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095901-B1 | PROCESS FOR THE PREPARATION OF (D) 2-(D-METHOXY-2-NAPHTHYL) PROPIONIC ACID AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AND NEW INTERMEDIATES THEREFOR | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1992-09-09 | — | — | EP | disclosed |
| US-5023365-A | Process for preparing an intermediate | ZAMBON GROUP S.P.A. (IT) | 1991-06-11 | — | — | US | disclosed |
| EP-0254971-B1 | CARBOXYLIC ACID SYNTHESIS PROCESS | ZAMBON S.p.A. (IT) | 1991-05-02 | — | — | EP | disclosed |
| US-4937379-A | Carboxylic acid synthesis process | ZAMBON S.P.A. (IT) | 1990-06-26 | — | — | US | disclosed |
| EP-0254971-A1 | Carboxylic acid synthesis process | ZAMBON S.p.A. (IT) | 1988-02-03 | — | — | EP | disclosed |
| US-4723033-A | REACTING ALPHA METAL ACID DERIVATIVE AND ARYL HALIDE WITH OPTICALLY ACTIVE CATALYST | SYNTEX PHARMACEUTICALS INTERNATIONAL LTD. (BM) | 1988-02-02 | — | — | US | disclosed |
| EP-0110671-B1 | PREPARATION OF OPTICALLY ACTIVE ALPHA-ARYLALKANOIC ACIDS AND PRECURSORS THEREOF | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1986-05-21 | — | — | EP | disclosed |
| EP-0110671-A1 | Preparation of optically active alpha-arylalkanoic acids and precursors thereof | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1984-06-13 | — | — | EP | disclosed |
| EP-0095901-A1 | Process for the preparation of (d) 2-(d-methoxy-2-naphthyl) propionic acid and pharmaceutically acceptable salts thereof and new intermediates therefor | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1983-12-07 | — | — | EP | disclosed |
| US-3994968-A | 2-(5'-Halo-6'-methoxynaphth-2'-yl)-acrylic acid | SYNTEX CORPORATION (PM) | 1976-11-30 | — | — | US | disclosed |
| US-3960957-A | 2-(6'-methoxynaphth-2'yl) propionaldoxime and 5'-halo derivatives thereof | SYNTEX CORPORATION (PM) | 1976-06-01 | — | — | US | disclosed |
| US-3952012-A | MULTISTAGE | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-04-20 | — | — | US | disclosed |