Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716459 | 0.83 | RIPK1 (0.49) | RIPK1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL4461404 | 0.79 | SMN1; SMN2 (0.51) | BRD4SMN1; SMN2NPC1RAB9APOLB | |
| Hydrochloric Acid SCHEMBL8763040 | 0.78 | SMN1; SMN2 (0.50) | BRD4SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL2222434 | 0.76 | SMN1; SMN2 (0.60) | BRD4SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL4956054 | 0.75 | CA12 (0.50) | NPC1RAB9APOLBLMNAMAPT | |
| SCHEMBL6331207 | 0.75 | SMN1; SMN2 (0.62) | BRD4SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL6368689 | 0.75 | RAB9A (0.38) | BRD4SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL236205 | 0.74 | HPGD (0.56) | SMN1; SMN2NPC1RAB9APOLBMAPT | |
| SCHEMBL11792109 | 0.74 | SMN1; SMN2 (0.61) | BRD4SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL5167397 | 0.73 | BRD4 (0.40) | RIPK1BRD4SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175294-A | For treatment of bone disorders | ADIR ET COMPAGNIE (FR) | 1992-12-29 | — | — | US | disclosed |
| US-5061704-A | PATHOLOGIES INVOLVING LOSS OF BONE TISSUE | ADIR ET COMPAGNIE (FR) | 1991-10-29 | — | — | US | disclosed |