SCHEMBL9716579

SCHEMBL9716579

CO[SiH](OC)C(C)C(C)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.36
TAAR1 Q96RJ0 4/20 0.35
ALDH1A1 P00352 2/20 0.35
THRB P10828 1/20 0.35
ADRA2A P08913 1/20 0.34
ADRA2C P18825 1/20 0.34
CYP2D6 P10635 1/20 0.34
LMNA P02545 1/20 0.34
HIF1A Q16665 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CACNA2D1 P54289 1/20 0.33
CACNB2 Q08289 1/20 0.33
CACNA1C Q13936 1/20 0.33
RAB9A P51151 1/20 0.33
MIF P14174 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL296207 0.79 KMT2A (0.40) KMT2ATAAR1ALDH1A1THRBADRA2A
SCHEMBL9716570 0.76 HKDC1 (0.43) KMT2ATAAR1ADRA2ACYP2D6LMNA
SCHEMBL9090719 0.75 MME (0.35) KMT2ATAAR1ALDH1A1LMNAHIF1A
SCHEMBL9091889 0.75 AOC3 (0.38) TAAR1ADRA2ACYP2D6LMNASMN1; SMN2
SCHEMBL10568864 0.75 KMT2A (0.40) KMT2ATAAR1ALDH1A1THRBLMNA
SCHEMBL19809329 0.73 KMT2A (0.43) KMT2AALDH1A1ADRA2AADRA2CCYP2D6
SCHEMBL908216 0.72 TAAR1 (0.50) TAAR1ALDH1A1ADRA2AADRA2CCYP2D6
SCHEMBL467677 0.71 KMT2A (0.38) KMT2ATAAR1ALDH1A1THRBMEN1
SCHEMBL2202411 0.71 TSHR (0.44) KMT2AALDH1A1MEN1MAPTMAPK1
SCHEMBL63868 0.71 DPP4 (0.44) KMT2ATAAR1ALDH1A1ADRA2AADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0282341-B1 PROCESS FOR POLYMERIZATION OF OLEFINS AND POLYMERIZATION CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-05-20 EP disclosed
EP-0455313-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-11-06 EP disclosed
US-5028671-A Using coordination catalyst contining magnesium, titanium, halogen compounds with organoaluminum and organosilicon compounds MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-07-02 US disclosed
EP-0282341-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-14 EP disclosed