SCHEMBL9716570

SCHEMBL9716570

CCC(c1ccccc1)C(C)[SiH](OC)OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HKDC1 Q2TB90 1/20 0.43
TAAR1 Q96RJ0 3/20 0.41
LMNA P02545 3/20 0.39
TRPA1 O75762 1/20 0.36
PGR P06401 2/20 0.35
SLC6A2 P23975 2/20 0.35
SLC6A3 Q01959 2/20 0.35
ESR1 P03372 1/20 0.35
CYP1A2 P05177 1/20 0.35
CHRM2 P08172 1/20 0.35
CYP3A4 P08684 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
AR P10275 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
CHRM1 P11229 1/20 0.35
CYP2C9 P11712 1/20 0.35
ALOX15 P16050 1/20 0.35
DRD1 P21728 1/20 0.35
TBXA2R P21731 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9716579 0.76 KMT2A (0.36) TAAR1LMNACYP2D6MAPTMEN1
SCHEMBL4071581 0.75 HKDC1 (0.65) HKDC1TAAR1LMNATRPA1PGR
SCHEMBL705765 0.75 LMNA (0.43) HKDC1TAAR1LMNATRPA1TDP1
SCHEMBL598978 0.73 TAAR1 (0.64) HKDC1TAAR1LMNATRPA1PGR
SCHEMBL296207 0.73 KMT2A (0.40) TAAR1LMNACYP2D6MAPTMEN1
SCHEMBL28218827 0.72 MMP8 (0.37) TAAR1LMNATRPA1KMT2AMMP8
SCHEMBL22009966 0.71 HKDC1 (0.52) HKDC1TAAR1LMNATRPA1PGR
SCHEMBL10831868 0.71 HKDC1 (0.52) HKDC1TAAR1LMNATRPA1PGR
SCHEMBL6547351 0.71 HKDC1 (0.52) HKDC1TAAR1LMNATRPA1PGR
SCHEMBL3861713 0.71 HKDC1 (0.55) HKDC1TAAR1LMNATRPA1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0282341-B1 PROCESS FOR POLYMERIZATION OF OLEFINS AND POLYMERIZATION CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-05-20 EP disclosed
EP-0455313-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-11-06 EP disclosed
US-5028671-A Using coordination catalyst contining magnesium, titanium, halogen compounds with organoaluminum and organosilicon compounds MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-07-02 US disclosed
EP-0282341-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-14 EP disclosed