Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716798 | 1.00 | ALDH1A1 (0.38) | ALDH1A1ATMHCAR2SLC1A2SLC1A1 | |
| SCHEMBL9716610 | 0.95 | GSR (0.39) | ALDH1A1ATMHCAR2SLC1A2SLC1A1 | |
| SCHEMBL9716606 | 0.95 | GSR (0.39) | ALDH1A1ATMHCAR2SLC1A2SLC1A1 | |
| SCHEMBL16862534 | 0.93 | ALDH1A1 (0.35) | ALDH1A1ATMHCAR2SLC1A2SLC1A1 | |
| SCHEMBL3826716 | 0.87 | ALDH1A1 (0.49) | ALDH1A1TSHRITGB3ITGA2BCYP3A4 | |
| SCHEMBL9716642 | 0.86 | CYP1A2 (0.42) | ALDH1A1SLC1A2SLC1A1SLC1A3CPB2 | |
| SCHEMBL9716651 | 0.86 | CYP1A2 (0.42) | ALDH1A1SLC1A2SLC1A1SLC1A3CPB2 | |
| SCHEMBL9716597 | 0.81 | CPB2 (0.46) | ALDH1A1SLC1A2SLC1A1GRIK1GRIK2 | |
| SCHEMBL9716594 | 0.81 | CPB2 (0.46) | ALDH1A1SLC1A2SLC1A1GRIK1GRIK2 | |
| SCHEMBL5422105 | 0.80 | ALDH1A1 (0.41) | ALDH1A1ATMHCAR2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |