Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996708 | 0.86 | NR4A1 (0.41) | NR4A1NR4A2NR4A3PTPN1CDC25B | |
| SCHEMBL3792155 | 0.79 | NR4A1 (0.53) | NR4A1NR4A2NR4A3PTPN1CDC25B | |
| SCHEMBL31060098 | 0.79 | NR4A1 (0.53) | NR4A1NR4A2NR4A3PTPN1CDC25B | |
| SCHEMBL9548533 | 0.78 | NR4A1 (0.60) | NR4A1NR4A2NR4A3PTPN1CDC25B | |
| SCHEMBL6570853 | 0.78 | KMT2A (0.51) | TP53MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11833560 | 0.77 | NR4A1 (0.58) | NR4A1NR4A2NR4A3PTPN1CDC25B | |
| Hydrochloric Acid SCHEMBL6927453 | 0.76 | NR4A1 (0.49) | NR4A1NR4A2NR4A3PTPN1CDC25B | |
| Hydrochloric Acid SCHEMBL11865419 | 0.76 | NR4A1 (0.56) | NR4A1NR4A2NR4A3PTPN1CDC25B | |
| SCHEMBL9303595 | 0.76 | POLB (0.60) | NR4A1NR4A2NR4A3PTPN1CDC25B | |
| SCHEMBL698882 | 0.74 | ADRA2C (0.64) | TDP1MEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |