Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | EPOR | P19235 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716737 | 0.96 | ALDH1A1 (0.38) | F2ALDH1A1SMN1; SMN2ADRA2CKMT2A | |
| SCHEMBL9716611 | 0.87 | F2 (0.40) | F2GSRRNPEPCPB2ADRA2C | |
| SCHEMBL9716619 | 0.87 | F2 (0.40) | F2GSRRNPEPCPB2ADRA2C | |
| SCHEMBL9716819 | 0.87 | F2 (0.40) | F2GSRRNPEPCPB2ADRA2C | |
| SCHEMBL9716829 | 0.87 | F2 (0.40) | F2GSRRNPEPCPB2ADRA2C | |
| SCHEMBL9716623 | 0.87 | F2 (0.50) | F2GSRRNPEPCPB2ADRA2C | |
| SCHEMBL1387992 | 0.87 | F2 (0.50) | F2GSRRNPEPCPB2ADRA2C | |
| SCHEMBL7321837 | 0.87 | F2 (0.50) | F2GSRRNPEPCPB2ADRA2C | |
| SCHEMBL9716633 | 0.82 | ADRA2C (0.38) | F2GSRRNPEPCPB2ADRA2C | |
| SCHEMBL9716649 | 0.82 | ADRA2C (0.38) | F2GSRRNPEPCPB2ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |