Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 7/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716799 | 0.82 | BCL2 (0.48) | BCL2SIGMAR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9716709 | 0.81 | BCL2 (0.50) | BCL2SIGMAR1SMN1; SMN2HPGDCHRM2 | |
| SCHEMBL9716867 | 0.81 | BCL2 (0.50) | BCL2SIGMAR1SMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL9716800 | 0.80 | BCL2 (0.49) | BCL2SIGMAR1KDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL9716801 | 0.80 | SIGMAR1 (0.62) | BCL2SIGMAR1ALDH1A1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9716825 | 0.79 | CHRM4 (0.62) | BCL2SIGMAR1ALDH1A1KDM4ESMN1; SMN2 | |
| Maleic Acid SCHEMBL9716788 | 0.78 | THRB (0.42) | BCL2SIGMAR1ALDH1A1SMN1; SMN2TDP1 | |
| Fumaric Acid SCHEMBL9716794 | 0.78 | THRB (0.42) | BCL2SIGMAR1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL9716774 | 0.77 | SIGMAR1 (0.55) | BCL2SIGMAR1ALDH1A1SMN1; SMN2CHRM2 | |
| Fumaric Acid SCHEMBL9716769 | 0.75 | BCL2 (0.45) | BCL2SIGMAR1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089529-A | Antiarrhythmia agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-02-18 | — | — | US | claimed |
| US-5089529-A | Antiarrhythmia agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-02-18 | — | — | US | disclosed |