Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
| ▸ | PRF1 | P14222 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716856 | 0.82 | — | — | |
| SCHEMBL10622539 | 0.82 | NR1H2 (0.36) | NR1H2NR1H3 | |
| SCHEMBL9716901 | 0.82 | ACHE (0.38) | NPC1TNFPKMRAB9ACDK5 | |
| SCHEMBL7634520 | 0.73 | NR1H2 (0.41) | NR1H2NR1H3HPGD | |
| SCHEMBL7635129 | 0.73 | NR1H2 (0.41) | NR1H2NR1H3HPGD | |
| SCHEMBL7631139 | 0.71 | NR1H2 (0.42) | NR1H2NR1H3HPGD | |
| SCHEMBL124710 | 0.70 | KMT2A (0.49) | NPC1TNFPKMRAB9ACDK5 | |
| SCHEMBL7631205 | 0.70 | NR1H2 (0.39) | NR1H2NR1H3HPGD | |
| SCHEMBL7634060 | 0.69 | NR1H2 (0.38) | NR1H2NR1H3RAB9AHPGD | |
| SCHEMBL7633886 | 0.69 | NR1H2 (0.41) | NR1H2NR1H3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239961-B1 | A SILICONE RUBBER COMPOSITION | Shin-Etsu Chemical Co., Ltd. (JP) | 1992-10-21 | — | — | EP | disclosed |
| EP-0278731-A2 | A silicone rubber composition | Shin-Etsu Chemical Co., Ltd. (JP) | 1988-08-17 | — | — | EP | disclosed |
| US-4755554-A | Silicone rubber composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-05 | — | — | US | disclosed |
| EP-0239961-A2 | A silicone rubber composition | Shin-Etsu Chemical Co., Ltd. (JP) | 1987-10-07 | — | — | EP | disclosed |