Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716898 | 0.82 | NR1H2 (0.37) | HPGDRAB9ANPC1TNFPKM | |
| SCHEMBL5012568 | 0.82 | ACHE (0.33) | ACHEHPGDRAB9ANPC1TNF | |
| SCHEMBL9716853 | 0.81 | ACHE (0.38) | ACHEHPGDCA12CA1CA2 | |
| SCHEMBL9726813 | 0.81 | SMN1; SMN2 (0.42) | ACHEHPGDRAB9ANPC1KMT2A | |
| SCHEMBL9730784 | 0.81 | RXRB (0.47) | ACHEHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL9716881 | 0.79 | ACHE (0.39) | ACHEHPGDRAB9ANPC1MEN1 | |
| SCHEMBL10627018 | 0.79 | ALDH1A1 (0.41) | HPGDRAB9ANPC1PKMMEN1 | |
| SCHEMBL124710 | 0.76 | KMT2A (0.49) | RAB9ANPC1TNFPKMCDK5 | |
| SCHEMBL6464548 | 0.75 | CYP3A4 (0.36) | ACHEHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL9279020 | 0.74 | LMNA (0.50) | ACHEHPGDMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239961-B1 | A SILICONE RUBBER COMPOSITION | Shin-Etsu Chemical Co., Ltd. (JP) | 1992-10-21 | — | — | EP | claimed |
| EP-0278731-A2 | A silicone rubber composition | Shin-Etsu Chemical Co., Ltd. (JP) | 1988-08-17 | — | — | EP | claimed |
| US-4755554-A | Silicone rubber composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-05 | — | — | US | claimed |
| EP-0239961-A2 | A silicone rubber composition | Shin-Etsu Chemical Co., Ltd. (JP) | 1987-10-07 | — | — | EP | claimed |
| EP-0239961-B1 | A SILICONE RUBBER COMPOSITION | Shin-Etsu Chemical Co., Ltd. (JP) | 1992-10-21 | — | — | EP | disclosed |
| EP-0278731-A2 | A silicone rubber composition | Shin-Etsu Chemical Co., Ltd. (JP) | 1988-08-17 | — | — | EP | disclosed |
| EP-0278731-A2 | A silicone rubber composition | Shin-Etsu Chemical Co., Ltd. (JP) | 1988-08-17 | — | — | EP | disclosed |
| US-4755554-A | Silicone rubber composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-05 | — | — | US | disclosed |
| EP-0239961-A2 | A silicone rubber composition | Shin-Etsu Chemical Co., Ltd. (JP) | 1987-10-07 | — | — | EP | disclosed |