Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11025136 | 0.81 | ALDH1A1 (0.50) | ALDH1A1RAB9ANPC1KDM4EMAPT | |
| SCHEMBL21091032 | 0.80 | ALDH1A1 (0.51) | ALDH1A1LMNARAB9ANPC1KDM4E | |
| SCHEMBL968101 | 0.78 | KDM4E (0.61) | ALDH1A1RAB9ANPC1KDM4EMAPT | |
| SCHEMBL14424576 | 0.78 | MAPT (0.35) | ALDH1A1LMNARAB9ANPC1KDM4E | |
| SCHEMBL970693 | 0.77 | ALDH1A1 (0.62) | ALDH1A1LMNARAB9ANPC1KDM4E | |
| SCHEMBL22469017 | 0.77 | GUSB (0.46) | ALDH1A1RAB9AKDM4EGAAHPGD | |
| SCHEMBL8046899 | 0.77 | HDAC1 (0.43) | ALDH1A1LMNARAB9ANPC1KDM4E | |
| SCHEMBL11609747 | 0.77 | ALDH1A1 (0.54) | ALDH1A1LMNARAB9ANPC1KDM4E | |
| SCHEMBL11565050 | 0.77 | ALDH1A1 (0.49) | ALDH1A1LMNARAB9ANPC1KDM4E | |
| SCHEMBL11332564 | 0.77 | ALDH1A1 (0.65) | ALDH1A1LMNARAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483412-B | Synthetic method of rosuvastatin tert-butyl ester | 安徽省庆云医药股份有限公司 | 2020-06-26 | — | — | CN | disclosed |
| CN-104292224-B | Containing replacing 1,3,4-thiophene () diazole thioether benzothiazole amide derivatives and its preparation method and application | 贵州大学 | 2016-07-06 | — | — | CN | disclosed |
| CN-104292224-A | Benzothiazole amide derivatives containing substituted 1,3,4-thiadiazole (oxadiazole) thioether as well as preparation method and application of derivatives | UNIV GUIZHOU | 2015-01-21 | — | — | CN | disclosed |
| US-7871982-B2 | Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-20090156512-A1 | potent activity against resistant pneumococci | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
| EP-1970377-A1 | LINCOMYCIN DERIVATIVE AND ANTIBACTERIAL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2008-09-17 | — | — | EP | disclosed |
| US-20070184383-A1 | Photosensitive composition, photosensitive planographic printing plate material, and recording method of planographic printing plate material | KONICA MINOLTA MEDICAL & GRAPHIC, INC. | 2007-08-09 | — | — | US | disclosed |
| US-20070184383-A1 | Photosensitive composition, photosensitive planographic printing plate material, and recording method of planographic printing plate material | KONICA MINOLTA MEDICAL & GRAPHIC, INC. | 2007-08-09 | — | — | US | disclosed |
| EP-0565459-B1 | Novel photographic developing solution and use thereof in the high contrast development of nucleated photographic elements | EASTMAN KODAK CO (US) | 1998-09-16 | — | — | EP | disclosed |
| US-5457011-A | Containing polyoxyalkylated phosphate ester to inhibit sludge formation | EASTMAN KODAK COMPANY (US) | 1995-10-10 | — | — | US | disclosed |
| US-5264323-A | Hydrazine nucleation agent with developers of ascorbic acid and carbonate buffers | EASTMAN KODAK COMPANY (US) | 1993-11-23 | — | — | US | disclosed |
| EP-0565459-A2 | Novel photographic developing solution and use thereof in the high contrast development of nucleated photographic elements | EASTMAN KODAK COMPANY (US) | 1993-10-13 | — | — | EP | disclosed |
| US-5236816-A | Hydroquinone-free | EASTMAN KODAK COMPANY (US) | 1993-08-17 | — | — | US | disclosed |
| EP-0428455-A2 | Photographic developing solution for use with fore-hardened X-ray films | EASTMAN KODAK COMPANY (US) | 1991-05-22 | — | — | EP | disclosed |
| EP-0267264-B1 | HIGH CONTRAST DEVELOPMENT OF PHOTOGRAPHIC ELEMENTS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1990-07-25 | — | — | EP | disclosed |
| EP-0267264-A1 | HIGH CONTRAST DEVELOPMENT OF PHOTOGRAPHIC ELEMENTS. | EASTMAN KODAK CO (US) | 1988-05-18 | — | — | EP | disclosed |
| WO-1987007039-A2 | HIGH CONTRAST DEVELOPMENT OF PHOTOGRAPHIC ELEMENTS | EASTMAN KODAK COMPANY (US) | 1987-11-19 | — | — | WO | disclosed |
| EP-0032456-B1 | METHOD FOR HIGH CONTRAST DEVELOPMENT OF PHOTOGRAPHIC ELEMENTS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1983-02-02 | — | — | EP | disclosed |
| EP-0032456-A1 | Method for high contrast development of photographic elements | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1981-07-22 | — | — | EP | disclosed |
| US-4269929-A | USING AN AQUEOUS ALKALINE SOLUTION CONTAINING DIHYDROXYBENZENE AND 3-PYRAZOLIDONE DEVELOPERS, A SULFITE PRESERVATIVE AND A CONTRAST-PROMOTING AMINE IN THE PRESENCE OF A HYDRAZIDE; LITHOGRAPHY | EASTMAN KODAK COMPANY (US) | 1981-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156512-A1 | potent activity against resistant pneumococci | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NAT1, NPM1 | ALDH1A1 2976/4885LMNA 48/4885RAB9A 377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.