Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | DDX3X | O00571 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL971700 | 0.81 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1KDM4EGAASMN1; SMN2 | |
| SCHEMBL8042754 | 0.79 | SMN1; SMN2 (0.39) | ALDH1A1KDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL968101 | 0.78 | KDM4E (0.61) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL1207261 | 0.78 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1KDM4EGAASMN1; SMN2 | |
| SCHEMBL1206577 | 0.77 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1KDM4EGAASMN1; SMN2 | |
| SCHEMBL22469017 | 0.77 | GUSB (0.46) | ALDH1A1KDM4EGAASMN1; SMN2RAB9A | |
| SCHEMBL8046899 | 0.77 | HDAC1 (0.43) | ALDH1A1KDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL970693 | 0.77 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL971940 | 0.77 | KDM4E (0.66) | ALDH1A1KDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL969373 | 0.77 | KDM4E (0.42) | ALDH1A1KDM4EGAASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050261-B1 | MOULDING MASSES STABILIZED AGAINST THERMOLYSIS WITH A LOW MONOMER CONTENT | BAYER AG (DE) | 1985-08-14 | — | — | EP | disclosed |
| EP-0050261-A1 | Moulding masses stabilized against thermolysis with a low monomer content | BAYER AG (DE) | 1982-04-28 | — | — | EP | disclosed |